Human DNA ligases: a comprehensive new look for cancer therapy.

Singh, Deependra Kumar; Krishna, Shagun; Chandra, Sharat; Shameem, Mohammad; Deshmukh, Amit Laxmikant; Banerjee, Dibyendu

Singh, Deependra Kumar; Krishna, Shagun; Chandra, Sharat; Shameem, Mohammad; Deshmukh, Amit Laxmikant; Banerjee, Dibyendu.

Affiliation

Singh DK; CSIR-Central Drug Research Institute, B.S. 10/1, Janakipuram Extension, Sitapur Road, Lucknow, 226021, Uttar Pradesh, India.

Med Res Rev ; 34(3): 567-95, 2014 May.

Article in En | MEDLINE | ID: mdl-23959747

Subject(s)

DNA Ligases/metabolism; Neoplasms/enzymology; Neoplasms/therapy; Amino Acid Sequence; DNA Ligases/antagonists & inhibitors; DNA Ligases/chemistry; Enzyme Inhibitors/chemistry; Enzyme Inhibitors/classification; Enzyme Inhibitors/pharmacology; Humans; Molecular Sequence Data; Molecular Targeted Therapy

Key words

DNA ligase; cancer drug; cancer target; inhibitor; ligase; ligase inhibitor

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Full text: 1 Database: MEDLINE Main subject: DNA Ligases / Neoplasms Limits: Humans Language: En Journal: Med Res Rev Year: 2014 Type: Article Affiliation country: India

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