Cotranscriptional recruitment of RNA exosome cofactors Rrp47p and Mpp6p and two distinct Trf-Air-Mtr4 polyadenylation (TRAMP) complexes assists the exonuclease Rrp6p in the targeting and degradation of an aberrant messenger ribonucleoprotein particle (mRNP) in yeast.

Stuparevic, Igor; Mosrin-Huaman, Christine; Hervouet-Coste, Nadège; Remenaric, Mateja; Rahmouni, A Rachid

Stuparevic, Igor; Mosrin-Huaman, Christine; Hervouet-Coste, Nadège; Remenaric, Mateja; Rahmouni, A Rachid.

Affiliation

Stuparevic I; From the Centre de Biophysique Moléculaire, Unité Propre de Recherche (UPR) 4301 du CNRS, rue Charles Sadron, 45071 Orléans, France.

J Biol Chem ; 288(44): 31816-29, 2013 Nov 01.

Article in En | MEDLINE | ID: mdl-24047896

Subject(s)

Adaptor Proteins, Signal Transducing/metabolism; DEAD-box RNA Helicases/metabolism; DNA-Binding Proteins/metabolism; DNA-Directed DNA Polymerase/metabolism; DNA-Directed RNA Polymerases/metabolism; Exosome Multienzyme Ribonuclease Complex/metabolism; Multienzyme Complexes/metabolism; Nuclear Proteins/metabolism; RNA Stability/physiology; RNA, Fungal/metabolism; RNA-Binding Proteins/metabolism; Ribonucleoproteins/metabolism; Saccharomyces cerevisiae Proteins/metabolism; Saccharomyces cerevisiae/metabolism; Adaptor Proteins, Signal Transducing/genetics; DEAD-box RNA Helicases/genetics; DNA-Binding Proteins/genetics; DNA-Directed DNA Polymerase/genetics; DNA-Directed RNA Polymerases/genetics; Enzyme Stability/physiology; Exosome Multienzyme Ribonuclease Complex/genetics; Multienzyme Complexes/genetics; Nuclear Proteins/genetics; RNA, Fungal/genetics; RNA-Binding Proteins/genetics; Ribonucleoproteins/genetics; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae Proteins/genetics

Key words

RNA; RNA Metabolism; RNA Processing; mRNA; mRNA Decay

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Full text: 1 Database: MEDLINE Main subject: Ribonucleoproteins / Saccharomyces cerevisiae / DNA-Directed RNA Polymerases / RNA, Fungal / Nuclear Proteins / RNA-Binding Proteins / RNA Stability / Saccharomyces cerevisiae Proteins / Adaptor Proteins, Signal Transducing / DNA-Binding Proteins Language: En Journal: J Biol Chem Year: 2013 Type: Article Affiliation country: France

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