Calpain-dependent cytoskeletal rearrangement exploited for anthrax toxin endocytosis.

Jeong, Sun-Young; Martchenko, Mikhail; Cohen, Stanley N

Jeong, Sun-Young; Martchenko, Mikhail; Cohen, Stanley N.

Affiliation

Jeong SY; Departments of Genetics and Medicine, Stanford University School of Medicine, Stanford, CA 94305.

Proc Natl Acad Sci U S A ; 110(42): E4007-15, 2013 Oct 15.

Article in En | MEDLINE | ID: mdl-24085852

Subject(s)

Antigens, Bacterial/metabolism; Bacillus anthracis/metabolism; Bacterial Toxins/metabolism; Calpain/biosynthesis; Cytoskeleton/metabolism; Endocytosis; Gene Expression Regulation; Amino Acid Substitution; Animals; Antigens, Bacterial/genetics; Bacillus anthracis/pathogenicity; Bacterial Toxins/genetics; Calpain/genetics; Cell Line; Cytoskeleton/genetics; Cytoskeleton/pathology; Down-Regulation/genetics; Focal Adhesions/genetics; Focal Adhesions/metabolism; Focal Adhesions/pathology; Mice; Mutation, Missense; Protein Transport/genetics; Receptors, Peptide/agonists; Receptors, Peptide/genetics; Receptors, Peptide/metabolism; Talin/genetics; Talin/metabolism

Key words

MDL28170; calpastatin; lethal factor

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Full text: 1 Database: MEDLINE Main subject: Bacillus anthracis / Bacterial Toxins / Cytoskeleton / Calpain / Gene Expression Regulation / Endocytosis / Antigens, Bacterial Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2013 Type: Article

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