Biocompatibility of silver nanoparticles and silver ions in primary human mesenchymal stem cells and osteoblasts.

Pauksch, Linda; Hartmann, Sonja; Rohnke, Marcus; Szalay, Gabor; Alt, Volker; Schnettler, Reinhard; Lips, Katrin S

Pauksch, Linda; Hartmann, Sonja; Rohnke, Marcus; Szalay, Gabor; Alt, Volker; Schnettler, Reinhard; Lips, Katrin S.

Affiliation

Pauksch L; Laboratory for Experimental Trauma Surgery, Justus-Liebig University Giessen, Schubertstrasse 81, 35392 Giessen, Germany.

Acta Biomater ; 10(1): 439-49, 2014 Jan.

Article in En | MEDLINE | ID: mdl-24095782

Subject(s)

Biocompatible Materials/pharmacology; Materials Testing; Mesenchymal Stem Cells/cytology; Metal Nanoparticles/chemistry; Osteoblasts/cytology; Silver/pharmacology; Adult; Alkaline Phosphatase/metabolism; Cell Count; Cell Proliferation/drug effects; Cell Shape/drug effects; Cell Survival/drug effects; Cell Survival/genetics; Gene Expression Regulation/drug effects; Humans; Ions; Mesenchymal Stem Cells/drug effects; Mesenchymal Stem Cells/enzymology; Mesenchymal Stem Cells/ultrastructure; Metal Nanoparticles/ultrastructure; Osteoblasts/drug effects; Osteoblasts/enzymology; Osteoblasts/ultrastructure; RNA, Messenger/genetics; RNA, Messenger/metabolism; Real-Time Polymerase Chain Reaction; Spectrophotometry, Ultraviolet

Key words

Bone cells; Nanoparticle uptake; Nanotoxicology; Risk assessment; Silver nanoparticles

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Full text: 1 Database: MEDLINE Main subject: Osteoblasts / Silver / Biocompatible Materials / Materials Testing / Metal Nanoparticles / Mesenchymal Stem Cells Type of study: Risk_factors_studies Limits: Adult / Humans Language: En Journal: Acta Biomater Year: 2014 Type: Article Affiliation country: Germany

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