The discovery of a reciprocal relationship between tyrosine-kinase signaling and cullin neddylation.

Friend, Samantha F; Peterson, Lisa K; Treacy, Eric; Stefanski, Adrianne L; Sosinowski, Tomasz; Pennock, Nathan D; Berger, Allison J; Winn, Virginia D; Dragone, Leonard L

Friend, Samantha F; Peterson, Lisa K; Treacy, Eric; Stefanski, Adrianne L; Sosinowski, Tomasz; Pennock, Nathan D; Berger, Allison J; Winn, Virginia D; Dragone, Leonard L.

Affiliation

Friend SF; Department of Pediatrics, University of Colorado School of Medicine, Denver, Colorado, United States of America ; Integrated Department of Immunology, University of Colorado School of Medicine and National Jewish Health, Denver, Colorado, United States of America.

PLoS One ; 8(10): e75200, 2013.

Article in En | MEDLINE | ID: mdl-24124476

Subject(s)

Cullin Proteins/metabolism; Protein-Tyrosine Kinases/metabolism; Animals; Cell Death/physiology; Cells, Cultured; Cullin Proteins/genetics; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Immunoblotting; Interleukin-2/metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Protein-Tyrosine Kinases/genetics; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction/genetics; Signal Transduction/physiology; T-Lymphocytes, Regulatory/metabolism

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Full text: 1 Database: MEDLINE Main subject: Protein-Tyrosine Kinases / Cullin Proteins Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2013 Type: Article Affiliation country: United States

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