Safety and pharmacokinetics of PF-04360365 following a single-dose intravenous infusion in Japanese subjects with mild-to-moderate Alzheimer's disease: a multicenter, randomized, double-blind, placebo-controlled, dose-escalation study.

Miyoshi, Izuru; Fujimoto, Yoko; Yamada, Masahito; Abe, Sadahiro; Zhao, Qinying; Cronenberger, Carol; Togo, Kanae; Ishibashi, Taro; Bednar, Martin M; Kupiec, James W; Binneman, Brendon

Miyoshi, Izuru; Fujimoto, Yoko; Yamada, Masahito; Abe, Sadahiro; Zhao, Qinying; Cronenberger, Carol; Togo, Kanae; Ishibashi, Taro; Bednar, Martin M; Kupiec, James W; Binneman, Brendon.

Int J Clin Pharmacol Ther ; 51(12): 911-23, 2013 Dec.

Article in En | MEDLINE | ID: mdl-24131736

Subject(s)

Alzheimer Disease/drug therapy; Antibodies, Monoclonal, Humanized/therapeutic use; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized/adverse effects; Antibodies, Monoclonal, Humanized/pharmacokinetics; Double-Blind Method; Female; Humans; Infusions, Intravenous; Male; Middle Aged

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Full text: 1 Database: MEDLINE Main subject: Alzheimer Disease / Antibodies, Monoclonal, Humanized Type of study: Clinical_trials Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Int J Clin Pharmacol Ther Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2013 Type: Article

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