Effects of prostacyclin on contractile properties of isolated mammalian cardiac muscle.
J Cardiovasc Pharmacol
; 7(5): 971-6, 1985.
Article
in En
| MEDLINE
| ID: mdl-2413310
ABSTRACT
We studied the influence of prostacyclin (PGI2) on the contractile performance of isolated mammalian ventricular muscle. PGI2 had no direct influence on myocardial contractility, as evidenced by experiments on single cardiac cells and papillary muscle. Moreover, PGI2 did not interfere with the inotropic action of isoproterenol. In comparison, neither prostaglandin E1 nor E2 appeared to have any cardiotonic action.
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Database:
MEDLINE
Main subject:
Prostaglandins E
/
Myocardial Contraction
Limits:
Animals
Language:
En
Journal:
J Cardiovasc Pharmacol
Year:
1985
Type:
Article