Identification of genes and pathways involved in the synthesis of Mead acid (20:3n-9), an indicator of essential fatty acid deficiency.

Ichi, Ikuyo; Kono, Nozomu; Arita, Yuka; Haga, Shizuka; Arisawa, Kotoko; Yamano, Misato; Nagase, Mana; Fujiwara, Yoko; Arai, Hiroyuki

Ichi, Ikuyo; Kono, Nozomu; Arita, Yuka; Haga, Shizuka; Arisawa, Kotoko; Yamano, Misato; Nagase, Mana; Fujiwara, Yoko; Arai, Hiroyuki.

Affiliation

Ichi I; Graduate School of Humanities and Sciences, Ochanomizu University, Tokyo 112-8610, Japan.

Biochim Biophys Acta ; 1841(1): 204-13, 2014 Jan.

Article in En | MEDLINE | ID: mdl-24184513

Subject(s)

8,11,14-Eicosatrienoic Acid/analogs & derivatives; Acetyltransferases/metabolism; Fatty Acid Desaturases/metabolism; Fatty Acids, Essential/deficiency; 8,11,14-Eicosatrienoic Acid/genetics; 8,11,14-Eicosatrienoic Acid/metabolism; Acetyltransferases/genetics; Animals; Biomarkers/metabolism; Fatty Acid Desaturases/genetics; Fatty Acid Elongases; Fatty Acids, Essential/biosynthesis; Gene Knockdown Techniques; Male; Mice; NIH 3T3 Cells

Key words

AA; ALA; Arachidonic acid; DHA; Docosahexaenoic acid; EFAD; EFAs; EPA; Eicosapentaenoic acid; Elongation of very long chain fatty acids; Elovl; Elovl5; Essential fatty acid deficiency; Essential fatty acids; FBS; Fads; Fatty acid desaturases; Fetal bovine serum; LA; Linoleic acid; Mead acid; PUFAs; Polyunsaturated fatty acid; Polyunsaturated fatty acids; α-Linolenic acid

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Full text: 1 Database: MEDLINE Main subject: Acetyltransferases / Fatty Acids, Essential / 8,11,14-Eicosatrienoic Acid / Fatty Acid Desaturases Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Biochim Biophys Acta Year: 2014 Type: Article Affiliation country: Japan

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