Phosphorylation of microtubule-binding protein Hec1 by mitotic kinase Aurora B specifies spindle checkpoint kinase Mps1 signaling at the kinetochore.

Zhu, Tongge; Dou, Zhen; Qin, Bo; Jin, Changjiang; Wang, Xinghui; Xu, Leilei; Wang, Zhaoyang; Zhu, Lijuan; Liu, Fusheng; Gao, Xinjiao; Ke, Yuwen; Wang, Zhiyong; Aikhionbare, Felix; Fu, Chuanhai; Ding, Xia; Yao, Xuebiao

Zhu, Tongge; Dou, Zhen; Qin, Bo; Jin, Changjiang; Wang, Xinghui; Xu, Leilei; Wang, Zhaoyang; Zhu, Lijuan; Liu, Fusheng; Gao, Xinjiao; Ke, Yuwen; Wang, Zhiyong; Aikhionbare, Felix; Fu, Chuanhai; Ding, Xia; Yao, Xuebiao.

Affiliation

Zhu T; From the Anhui Key Laboratory of Cellular Dynamics and Chemical Biology, University of Science and Technology of China, Hefei 230026, China.

J Biol Chem ; 288(50): 36149-59, 2013 Dec 13.

Article in En | MEDLINE | ID: mdl-24187132

Subject(s)

Aurora Kinase B/metabolism; Cell Cycle Proteins/metabolism; Kinetochores/metabolism; M Phase Cell Cycle Checkpoints; Microtubules/metabolism; Nuclear Proteins/metabolism; Protein Serine-Threonine Kinases/metabolism; Protein-Tyrosine Kinases/metabolism; Signal Transduction; Cell Cycle Checkpoints; Cytoskeletal Proteins; Gene Expression Regulation; HeLa Cells; Humans; Nuclear Proteins/chemistry; Phosphorylation; Protein Structure, Tertiary; Protein Transport

Key words

Cenp-e; Checkpoint; Checkpoint Control; Kinetochore; Mitosis; Mitotic Spindle; Phosphorylation

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Full text: 1 Database: MEDLINE Main subject: Protein-Tyrosine Kinases / Nuclear Proteins / Signal Transduction / Protein Serine-Threonine Kinases / Kinetochores / Cell Cycle Proteins / M Phase Cell Cycle Checkpoints / Aurora Kinase B / Microtubules Limits: Humans Language: En Journal: J Biol Chem Year: 2013 Type: Article Affiliation country: China

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