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TIM-4 glycoprotein-mediated degradation of dying tumor cells by autophagy leads to reduced antigen presentation and increased immune tolerance.
Baghdadi, Muhammad; Yoneda, Akihiro; Yamashina, Tsunaki; Nagao, Hiroko; Komohara, Yoshihiro; Nagai, Shigenori; Akiba, Hisaya; Foretz, Marc; Yoshiyama, Hironori; Kinoshita, Ichiro; Dosaka-Akita, Hirotoshi; Takeya, Motohiro; Viollet, Benoit; Yagita, Hideo; Jinushi, Masahisa.
Affiliation
  • Baghdadi M; Research Center for Infection-Associated Cancer, Institute for Genetic Medicine, Hokkaido University, Sapporo, 060-0815, Japan.
  • Yoneda A; Research Center for Infection-Associated Cancer, Institute for Genetic Medicine, Hokkaido University, Sapporo, 060-0815, Japan.
  • Yamashina T; Research Center for Infection-Associated Cancer, Institute for Genetic Medicine, Hokkaido University, Sapporo, 060-0815, Japan.
  • Nagao H; Research Center for Infection-Associated Cancer, Institute for Genetic Medicine, Hokkaido University, Sapporo, 060-0815, Japan.
  • Komohara Y; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, 860-8556, Japan.
  • Nagai S; Department of Molecular Immunology, Tokyo Medical and Dental University, Tokyo, 113-8549, Japan.
  • Akiba H; Department of Immunology, Juntendo University School of Medicine, Tokyo, 113-8421, Japan.
  • Foretz M; INSERM, U1016, Institut Cochin, Paris, 75014, France; CNRS, UMR8104, Paris, 75014, France; Université Paris Descartes, Sorbonne Paris Cité, 75014, France.
  • Yoshiyama H; Research Center for Infection-Associated Cancer, Institute for Genetic Medicine, Hokkaido University, Sapporo, 060-0815, Japan.
  • Kinoshita I; Department of Medical Oncology, Hokkaido University Graduate School of Medicine, Sapporo, 060-0815, Japan.
  • Dosaka-Akita H; Department of Medical Oncology, Hokkaido University Graduate School of Medicine, Sapporo, 060-0815, Japan.
  • Takeya M; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, 860-8556, Japan.
  • Viollet B; INSERM, U1016, Institut Cochin, Paris, 75014, France; CNRS, UMR8104, Paris, 75014, France; Université Paris Descartes, Sorbonne Paris Cité, 75014, France.
  • Yagita H; Department of Immunology, Juntendo University School of Medicine, Tokyo, 113-8421, Japan.
  • Jinushi M; Research Center for Infection-Associated Cancer, Institute for Genetic Medicine, Hokkaido University, Sapporo, 060-0815, Japan. Electronic address: jinushi@igm.hokudai.ac.jp.
Immunity ; 39(6): 1070-81, 2013 Dec 12.
Article in En | MEDLINE | ID: mdl-24315994
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Full text: 1 Database: MEDLINE Main subject: Autophagy / Antigen Presentation / Immune Tolerance / Macrophages / Membrane Proteins Limits: Animals Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2013 Type: Article Affiliation country: Japan
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Autophagy / Antigen Presentation / Immune Tolerance / Macrophages / Membrane Proteins Limits: Animals Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2013 Type: Article Affiliation country: Japan