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Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model.
Bard-Chapeau, Emilie A; Nguyen, Anh-Tuan; Rust, Alistair G; Sayadi, Ahmed; Lee, Philip; Chua, Belinda Q; New, Lee-Sun; de Jong, Johann; Ward, Jerrold M; Chin, Christopher Ky; Chew, Valerie; Toh, Han Chong; Abastado, Jean-Pierre; Benoukraf, Touati; Soong, Richie; Bard, Frederic A; Dupuy, Adam J; Johnson, Randy L; Radda, George K; Chan, Eric Cy; Wessels, Lodewyk Fa; Adams, David J; Jenkins, Nancy A; Copeland, Neal G.
Affiliation
  • Bard-Chapeau EA; Institute Molecular and Cell Biology, Agency for Science, Technology and Research (ASTAR), Biopolis, Singapore.
  • Nguyen AT; Institute Molecular and Cell Biology, Agency for Science, Technology and Research (ASTAR), Biopolis, Singapore.
  • Rust AG; Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1HH, UK.
  • Sayadi A; Institute Molecular and Cell Biology, Agency for Science, Technology and Research (ASTAR), Biopolis, Singapore.
  • Lee P; Clinical Imaging Research Centre, National University of Singapore, Centre for Translation Medicine, 14 Medical Drive, #B1-01, 117599, Singapore.
  • Chua BQ; Institute Molecular and Cell Biology, Agency for Science, Technology and Research (ASTAR), Biopolis, Singapore.
  • New LS; Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, 117543, Singapore.
  • de Jong J; Department of Molecular Carcinogenesis, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam.
  • Ward JM; Institute Molecular and Cell Biology, Agency for Science, Technology and Research (ASTAR), Biopolis, Singapore.
  • Chin CK; Institute Molecular and Cell Biology, Agency for Science, Technology and Research (ASTAR), Biopolis, Singapore.
  • Chew V; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (ASTAR), Biopolis, Singapore.
  • Toh HC; National Cancer Centre, Singapore.
  • Abastado JP; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (ASTAR), Biopolis, Singapore.
  • Benoukraf T; Cancer Science Institute of Singapore, National University of Singapore, Department of Pathology, National University Health System, Singapore.
  • Soong R; Cancer Science Institute of Singapore, National University of Singapore, Department of Pathology, National University Health System, Singapore.
  • Bard FA; Institute Molecular and Cell Biology, Agency for Science, Technology and Research (ASTAR), Biopolis, Singapore.
  • Dupuy AJ; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242.
  • Johnson RL; Department of Biochemistry and Molecular Biology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
  • Radda GK; Clinical Imaging Research Centre, National University of Singapore, Centre for Translation Medicine, 14 Medical Drive, #B1-01, 117599, Singapore.
  • Chan EC; Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, 117543, Singapore.
  • Wessels LF; Department of Molecular Carcinogenesis, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam.
  • Adams DJ; Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1HH, UK.
  • Jenkins NA; Institute Molecular and Cell Biology, Agency for Science, Technology and Research (ASTAR), Biopolis, Singapore.
  • Copeland NG; Institute Molecular and Cell Biology, Agency for Science, Technology and Research (ASTAR), Biopolis, Singapore.
Nat Genet ; 46(1): 24-32, 2014 Jan.
Article in En | MEDLINE | ID: mdl-24316982
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Full text: 1 Database: MEDLINE Main subject: Mutagenesis / Carcinoma, Hepatocellular / Hepatitis B, Chronic / Liver Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2014 Type: Article Affiliation country: Singapore
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Mutagenesis / Carcinoma, Hepatocellular / Hepatitis B, Chronic / Liver Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2014 Type: Article Affiliation country: Singapore