Amelioration of salt-induced vascular dysfunction in mesenteric arteries of Dahl salt-sensitive rats by missense mutation of extracellular superoxide dismutase.

Beyer, Andreas M; Raffai, Gabor; Weinberg, Brian D; Fredrich, Katherine; Rodgers, Matthew S; Geurts, Aron M; Jacob, Howard J; Dwinell, Melinda R; Lombard, Julian H

Beyer, Andreas M; Raffai, Gabor; Weinberg, Brian D; Fredrich, Katherine; Rodgers, Matthew S; Geurts, Aron M; Jacob, Howard J; Dwinell, Melinda R; Lombard, Julian H.

Affiliation

Beyer AM; Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin;

Am J Physiol Heart Circ Physiol ; 306(3): H339-47, 2014 Feb.

Article in En | MEDLINE | ID: mdl-24322611

Subject(s)

Mesenteric Arteries/enzymology; Mutation, Missense; Sodium Chloride, Dietary/toxicity; Superoxide Dismutase/metabolism; Acetylcholine/pharmacology; Animals; Aorta/metabolism; Aorta/physiopathology; Catalase/pharmacology; Mesenteric Arteries/drug effects; Mesenteric Arteries/physiopathology; NG-Nitroarginine Methyl Ester/pharmacology; Oxygen/metabolism; Phenylephrine/pharmacology; Polyethylene Glycols/pharmacology; Rats, Inbred Dahl; Sodium Chloride, Dietary/metabolism; Superoxide Dismutase/genetics; Vasodilation

Key words

endothelial function; endothelium; oxidant stress; reactive oxygen species; salt-sensitive hypertension; superoxide anion

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Full text: 1 Database: MEDLINE Main subject: Superoxide Dismutase / Sodium Chloride, Dietary / Mutation, Missense / Mesenteric Arteries Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2014 Type: Article

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