5-Aminoimidazole-4-carboxamide ribonucleoside induces differentiation of acute myeloid leukemia cells.

Lalic, Hrvoje; Dembitz, Vilma; Lukinovic-Skudar, Vesna; Banfic, Hrvoje; Visnjic, Dora

Lalic, Hrvoje; Dembitz, Vilma; Lukinovic-Skudar, Vesna; Banfic, Hrvoje; Visnjic, Dora.

Affiliation

Lalic H; Department of Physiology and Croatian Institute for Brain Research, School of Medicine, University of Zagreb , Croatia.

Leuk Lymphoma ; 55(10): 2375-83, 2014 Oct.

Article in En | MEDLINE | ID: mdl-24359245

Subject(s)

Aminoimidazole Carboxamide/analogs & derivatives; Cell Differentiation/drug effects; Leukemia, Myeloid, Acute/pathology; Ribonucleotides/pharmacology; Aminoimidazole Carboxamide/pharmacology; Apoptosis/drug effects; Cell Line, Tumor; Humans; Leukemia, Myeloid, Acute/metabolism; Mitogen-Activated Protein Kinases/metabolism; Signal Transduction/drug effects; Tumor Cells, Cultured

Key words

AICAR; differentiation markers; leukemia

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Full text: 1 Database: MEDLINE Main subject: Ribonucleotides / Leukemia, Myeloid, Acute / Cell Differentiation / Aminoimidazole Carboxamide Limits: Humans Language: En Journal: Leuk Lymphoma Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2014 Type: Article Affiliation country: Croatia

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