Enterotoxigenic Escherichia coli secretes a highly conserved mucin-degrading metalloprotease to effectively engage intestinal epithelial cells.

Luo, Qingwei; Kumar, Pardeep; Vickers, Tim J; Sheikh, Alaullah; Lewis, Warren G; Rasko, David A; Sistrunk, Jeticia; Fleckenstein, James M

Luo, Qingwei; Kumar, Pardeep; Vickers, Tim J; Sheikh, Alaullah; Lewis, Warren G; Rasko, David A; Sistrunk, Jeticia; Fleckenstein, James M.

Affiliation

Luo Q; Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, Missouri, USA.

Infect Immun ; 82(2): 509-21, 2014 Feb.

Article in En | MEDLINE | ID: mdl-24478067

Subject(s)

Enterotoxigenic Escherichia coli/enzymology; Enterotoxigenic Escherichia coli/metabolism; Epithelial Cells/microbiology; Escherichia coli Proteins/metabolism; Metalloproteases/metabolism; Mucin-2/metabolism; Mucin-3/metabolism; Animals; Cell Line; Disease Models, Animal; Escherichia coli Infections/microbiology; Humans; Hydrolysis; Mice; Virulence Factors/metabolism

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Full text: 1 Database: MEDLINE Main subject: Escherichia coli Proteins / Metalloproteases / Epithelial Cells / Enterotoxigenic Escherichia coli / Mucin-3 / Mucin-2 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Infect Immun Year: 2014 Type: Article Affiliation country: United States

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