Specific carotenoid intake is inversely associated with the risk of breast cancer among Chinese women.
Br J Nutr
; 111(9): 1686-95, 2014 May.
Article
in En
| MEDLINE
| ID: mdl-24502868
ABSTRACT
The protective effect of dietary carotenoid intake on the risk of breast cancer is inconclusive. Moreover, data on dietary carotenoids in relation to breast cancer in non-Western populations are scarce. The aim of the present study was to examine the association between dietary carotenoid intake and the risk of breast cancer among Chinese women. A total of 561 cases and 561 controls who were frequency matched by age (5-year interval) and residence were recruited in the present case-control study. Dietary intake information was collected by a face-to-face interview using a validated FFQ. The OR and 95 % CI were assessed by multivariate logistic regression after adjusting for various potential confounders. An inverse association was observed between the consumption of α-carotene, ß-carotene, ß-cryptoxanthin and lutein/zeaxanthin and the risk of breast cancer. The multivariate-adjusted OR for the highest quartile of intake compared with the lowest quartile of intake were 0·61 (95 % CI 0·43, 0·88) for α-carotene, 0·54 (95 % CI 0·38, 0·78) for ß-carotene, 0·38 (95 % CI 0·26, 0·52) for ß-cryptoxanthin and 0·49 (95 % CI 0·34, 0·71) for lutein/zeaxanthin. Lycopene intake was not found to be associated with the risk of breast cancer, with the adjusted OR of 0·89 (95 % CI 0·61, 1·30). These inverse associations were more evident among pre-menopausal women and women who were exposed to second-hand smoke. The protective effect of specific carotenoid intake was observed for all subtypes of hormone receptor status of breast cancer. The present study indicated that a greater intake of specific carotenoids was associated with a decreased risk of breast cancer among Chinese women residing in Guangdong.
Full text:
1
Database:
MEDLINE
Main subject:
Breast Neoplasms
/
Carotenoids
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Anticarcinogenic Agents
/
Diet
Type of study:
Clinical_trials
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Etiology_studies
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Observational_studies
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Qualitative_research
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Risk_factors_studies
Limits:
Adult
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Aged
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Female
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Humans
/
Middle aged
Country/Region as subject:
Asia
Language:
En
Journal:
Br J Nutr
Year:
2014
Type:
Article