Mice deficient in heparanase exhibit impaired dendritic cell migration and reduced airway inflammation.

Poon, Ivan K H; Goodall, Katharine J; Phipps, Simon; Chow, Jenny D Y; Pagler, Eloisa B; Andrews, Daniel M; Conlan, Carly L; Ryan, Gemma F; White, Julie A; Wong, Michael K L; Horan, Catherine; Matthaei, Klaus I; Smyth, Mark J; Hulett, Mark D

Poon, Ivan K H; Goodall, Katharine J; Phipps, Simon; Chow, Jenny D Y; Pagler, Eloisa B; Andrews, Daniel M; Conlan, Carly L; Ryan, Gemma F; White, Julie A; Wong, Michael K L; Horan, Catherine; Matthaei, Klaus I; Smyth, Mark J; Hulett, Mark D.

Affiliation

Poon IK; Department of Biochemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Australia.

Eur J Immunol ; 44(4): 1016-30, 2014 Apr.

Article in En | MEDLINE | ID: mdl-24532362

Subject(s)

Cell Movement/immunology; Dendritic Cells/immunology; Glucuronidase/immunology; Pneumonia/immunology; Animals; Blotting, Western; Cell Movement/genetics; Cells, Cultured; Dendritic Cells/metabolism; Female; Flow Cytometry; Gene Expression/genetics; Gene Expression/immunology; Glucuronidase/deficiency; Glucuronidase/genetics; Lymph Nodes/immunology; Lymph Nodes/metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Fluorescence; Pneumonia/genetics; Reverse Transcriptase Polymerase Chain Reaction; Skin/immunology; Skin/metabolism

Key words

Allergy; DC; Heparanase; Inflammation; Migration

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Full text: 1 Database: MEDLINE Main subject: Pneumonia / Dendritic Cells / Cell Movement / Glucuronidase Type of study: Prognostic_studies Limits: Animals Language: En Journal: Eur J Immunol Year: 2014 Type: Article Affiliation country: Australia

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