TLR-mediated STAT3 and ERK activation controls IL-10 secretion by human B cells.

Liu, Bi-Sheng; Cao, Yonghao; Huizinga, Tom W; Hafler, David A; Toes, Rene E M

Liu, Bi-Sheng; Cao, Yonghao; Huizinga, Tom W; Hafler, David A; Toes, Rene E M.

Affiliation

Liu BS; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

Eur J Immunol ; 44(7): 2121-9, 2014 Jul.

Article in En | MEDLINE | ID: mdl-24737107

Subject(s)

B-Lymphocytes/immunology; Extracellular Signal-Regulated MAP Kinases/physiology; Interleukin-10/biosynthesis; STAT3 Transcription Factor/physiology; Toll-Like Receptors/physiology; Cells, Cultured; Humans; Interferon-alpha/pharmacology; Phosphorylation; Toll-Like Receptor 7/physiology; Toll-Like Receptor 8/physiology; Toll-Like Receptor 9/physiology

Key words

B10 cells; IL-10-producing B cells; Regulatory B cells; Toll-like receptor; Type I interferon

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Full text: 1 Database: MEDLINE Main subject: B-Lymphocytes / Interleukin-10 / Extracellular Signal-Regulated MAP Kinases / STAT3 Transcription Factor / Toll-Like Receptors Type of study: Prognostic_studies Limits: Humans Language: En Journal: Eur J Immunol Year: 2014 Type: Article Affiliation country: Netherlands

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