Mesenteric lymph diversion abrogates 5-lipoxygenase activation in the kidney following trauma and hemorrhagic shock.

Stringham, John R; Moore, Ernest E; Gamboni, Fabia; Harr, Jeffrey N; Fragoso, Miguel; Chin, Theresa L; Carr, Caitlin E; Silliman, Christopher C; Banerjee, Anirban

Stringham, John R; Moore, Ernest E; Gamboni, Fabia; Harr, Jeffrey N; Fragoso, Miguel; Chin, Theresa L; Carr, Caitlin E; Silliman, Christopher C; Banerjee, Anirban.

J Trauma Acute Care Surg ; 76(5): 1214-21, 2014 May.

Article in En | MEDLINE | ID: mdl-24747451

Subject(s)

Acute Kidney Injury/enzymology; Acute Lung Injury/enzymology; Arachidonate 5-Lipoxygenase/metabolism; Kidney/enzymology; Multiple Organ Failure/metabolism; Shock, Hemorrhagic/enzymology; Wounds and Injuries/enzymology; Acute Kidney Injury/etiology; Acute Kidney Injury/physiopathology; Acute Lung Injury/etiology; Acute Lung Injury/physiopathology; Animals; Arachidonate 5-Lipoxygenase/urine; Biomarkers/metabolism; Biomarkers/urine; Disease Models, Animal; Enzyme Activation/physiology; Injury Severity Score; Leukotrienes/metabolism; Leukotrienes/urine; Lymph Nodes/enzymology; Lymph Nodes/metabolism; Male; Mesentery/enzymology; Mesentery/metabolism; Multiple Organ Failure/etiology; Multiple Organ Failure/physiopathology; Random Allocation; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Shock, Hemorrhagic/diagnosis; Shock, Hemorrhagic/etiology; Wounds and Injuries/complications; Wounds and Injuries/diagnosis

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Full text: 1 Database: MEDLINE Main subject: Shock, Hemorrhagic / Wounds and Injuries / Arachidonate 5-Lipoxygenase / Acute Lung Injury / Acute Kidney Injury / Kidney / Multiple Organ Failure Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Trauma Acute Care Surg Year: 2014 Type: Article

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