On-line determination of 4-nitrophenol by combining molecularly imprinted solid-phase extraction and fiber-optic spectrophotometry.
J Sep Sci
; 37(14): 1873-9, 2014 Jul.
Article
in En
| MEDLINE
| ID: mdl-24757081
ABSTRACT
In the present paper, we describe a new on-line SPE system where molecular imprinting, fiber-optic detection and flow injection analysis were combined for the first time. This new system has been applied for the on line detection of 4-nitrophenol (4-NP). Initially, molecularly imprinted polymers (MIP) have been prepared for the selective extraction of 4-NP using 4-vinylpyridine and ethylene glycol dimethacrylate as functional and cross-linking monomers, respectively. Selective extraction was achieved using the designed MIP with 97% of recovery on imprinted polymer and 10% on control polymer. The system provided a high degree of accuracy, with RSDs varying between 0.7 and 1.39%. In respect of accuracy, reproducibility, and rapidity, this system is comparable with HPLC. In short, the system allows simple, fast, and accurate analyte determination with the possibility of future automation.
Full text:
1
Database:
MEDLINE
Language:
En
Journal:
J Sep Sci
Year:
2014
Type:
Article
Affiliation country:
Turkey