Regulation of endothelial progenitor cell differentiation and function by dimethylarginine dimethylaminohydrolase 2 in an asymmetric dimethylarginine-independent manner.

Yuan, Qiong; Bai, Yong-Ping; Shi, Rui-Zheng; Liu, Si-Yu; Chen, Xu-Meng; Chen, Lei; Li, Yuan-Jian; Hu, Chang-Ping

Yuan, Qiong; Bai, Yong-Ping; Shi, Rui-Zheng; Liu, Si-Yu; Chen, Xu-Meng; Chen, Lei; Li, Yuan-Jian; Hu, Chang-Ping.

Affiliation

Yuan Q; Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China; Department of Pharmacology, Medical College, Wuhan University of Science and Technology, Wuhan 430081, China.

Cell Biol Int ; 38(9): 1013-22, 2014 Sep.

Article in En | MEDLINE | ID: mdl-24764313

Subject(s)

Amidohydrolases/metabolism; Arginine/analogs & derivatives; Cell Differentiation/drug effects; Endothelial Progenitor Cells/drug effects; Amidohydrolases/antagonists & inhibitors; Amidohydrolases/genetics; Arginine/pharmacology; Cells, Cultured; Cellular Senescence; Endothelial Progenitor Cells/cytology; Endothelial Progenitor Cells/metabolism; Humans; RNA Interference; RNA, Messenger/metabolism; RNA, Small Interfering/metabolism; Sirtuin 1/genetics; Sirtuin 1/metabolism; Vascular Endothelial Growth Factor A/genetics; Vascular Endothelial Growth Factor A/metabolism; Vascular Endothelial Growth Factor Receptor-2/genetics; Vascular Endothelial Growth Factor Receptor-2/metabolism

Key words

SIRT1; dimethylarginine dimethylaminohydrolase; endothelial progenitor cells; senescence

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Full text: 1 Database: MEDLINE Main subject: Arginine / Cell Differentiation / Endothelial Progenitor Cells / Amidohydrolases Limits: Humans Language: En Journal: Cell Biol Int Year: 2014 Type: Article Affiliation country: China

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