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A low-affinity penicillin-binding protein 2x variant is required for heteroresistance in Streptococcus pneumoniae.
Engel, Hansjürg; Mika, Moana; Denapaite, Dalia; Hakenbeck, Regine; Mühlemann, Kathrin; Heller, Manfred; Hathaway, Lucy J; Hilty, Markus.
Affiliation
  • Engel H; Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.
  • Mika M; Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.
  • Denapaite D; Department of Microbiology, University of Kaiserslautern, Kaiserslautern, Germany.
  • Hakenbeck R; Department of Microbiology, University of Kaiserslautern, Kaiserslautern, Germany.
  • Mühlemann K; Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland Department of Infectious Diseases, University Hospital and University of Bern, Bern, Switzerland.
  • Heller M; Laboratory of Thrombosis Research, Department of Clinical Research, University of Bern, Bern, Switzerland.
  • Hathaway LJ; Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland.
  • Hilty M; Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland Department of Infectious Diseases, University Hospital and University of Bern, Bern, Switzerland markus.hilty@ifik.unibe.ch.
Antimicrob Agents Chemother ; 58(7): 3934-41, 2014 Jul.
Article in En | MEDLINE | ID: mdl-24777105
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Full text: 1 Database: MEDLINE Main subject: Streptococcus pneumoniae / Penicillin Resistance / Drug Resistance, Multiple, Bacterial / Penicillin-Binding Proteins Limits: Humans Language: En Journal: Antimicrob Agents Chemother Year: 2014 Type: Article Affiliation country: Switzerland
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Full text: 1 Database: MEDLINE Main subject: Streptococcus pneumoniae / Penicillin Resistance / Drug Resistance, Multiple, Bacterial / Penicillin-Binding Proteins Limits: Humans Language: En Journal: Antimicrob Agents Chemother Year: 2014 Type: Article Affiliation country: Switzerland