Caspase-12 ablation preserves muscle function in the mdx mouse.

Moorwood, Catherine; Barton, Elisabeth R

Moorwood, Catherine; Barton, Elisabeth R.

Affiliation

Moorwood C; Department of Anatomy and Cell Biology, University of Pennsylvania School of Dental Medicine, Philadelphia, PA, USA and Pennsylvania Muscle Institute, University of Pennsylvania, Philadelphia, PA, USA.
Barton ER; Department of Anatomy and Cell Biology, University of Pennsylvania School of Dental Medicine, Philadelphia, PA, USA and Pennsylvania Muscle Institute, University of Pennsylvania, Philadelphia, PA, USA erbarton@dental.upenn.edu.

Hum Mol Genet ; 23(20): 5325-41, 2014 Oct 15.

Article in En | MEDLINE | ID: mdl-24879640

Subject(s)

Caspase 12/genetics; Caspases, Initiator/genetics; Endoplasmic Reticulum Stress; Muscle, Skeletal/physiopathology; Muscular Dystrophy, Duchenne/physiopathology; Adolescent; Animals; Caspase 12/metabolism; Caspases, Initiator/metabolism; Child; Child, Preschool; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Female; Gene Expression Regulation; Heat-Shock Proteins/metabolism; Humans; Male; Mice; Mice, Inbred mdx; Mice, Transgenic; Muscle, Skeletal/metabolism; Muscular Dystrophy, Duchenne/genetics; Muscular Dystrophy, Duchenne/metabolism

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Full text: 1 Database: MEDLINE Main subject: Muscle, Skeletal / Muscular Dystrophy, Duchenne / Caspases, Initiator / Caspase 12 / Endoplasmic Reticulum Stress Limits: Adolescent / Animals / Child / Child, preschool / Female / Humans / Male Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2014 Type: Article Affiliation country: United States

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