Staphylococcus aureus hemolysin A disrupts cell-matrix adhesions in human airway epithelial cells.

Hermann, Ina; Räth, Susann; Ziesemer, Sabine; Volksdorf, Thomas; Dress, Regine J; Gutjahr, Melanie; Müller, Christian; Beule, Achim G; Hildebrandt, Jan-Peter

Hermann, Ina; Räth, Susann; Ziesemer, Sabine; Volksdorf, Thomas; Dress, Regine J; Gutjahr, Melanie; Müller, Christian; Beule, Achim G; Hildebrandt, Jan-Peter.

Affiliation

Hermann I; 1 Animal Physiology and Biochemistry, Zoological Institute, Ernst Moritz Arndt-University, Greifswald, Germany.

Am J Respir Cell Mol Biol ; 52(1): 14-24, 2015 Jan.

Article in En | MEDLINE | ID: mdl-24918472

Subject(s)

Epithelial Cells/metabolism; Extracellular Matrix/metabolism; Pneumonia, Staphylococcal/metabolism; Respiratory Mucosa/metabolism; Staphylococcus aureus/metabolism; Bacterial Toxins/genetics; Cell Adhesion/genetics; Cell Line; Epithelial Cells/pathology; Extracellular Matrix/genetics; Female; Focal Adhesion Kinase 1/genetics; Focal Adhesion Kinase 1/metabolism; Focal Adhesions/genetics; Focal Adhesions/metabolism; Focal Adhesions/pathology; Hemolysin Proteins/genetics; Humans; Male; Paxillin/genetics; Paxillin/metabolism; Phosphorylation/genetics; Pneumonia, Staphylococcal/genetics; Pneumonia, Staphylococcal/pathology; Respiratory Mucosa/pathology; Signal Transduction/genetics; Staphylococcus aureus/genetics; Vinculin/genetics; Vinculin/metabolism

Key words

Staphylococcus aureus; epithelial barrier function; focal adhesions; hemolysin A; human airway epithelial cells

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Full text: 1 Database: MEDLINE Main subject: Pneumonia, Staphylococcal / Staphylococcus aureus / Respiratory Mucosa / Epithelial Cells / Extracellular Matrix Type of study: Prognostic_studies Limits: Female / Humans / Male Language: En Journal: Am J Respir Cell Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2015 Type: Article Affiliation country: Germany

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