Radiation sensitization of tumor cells induced by shear stress: the roles of integrins and FAK.

Luo, Chi-Wen; Wu, Chia-Ching; Ch'ang, Hui-Ju

Luo, Chi-Wen; Wu, Chia-Ching; Ch'ang, Hui-Ju.

Affiliation

Luo CW; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.
Wu CC; Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Ch'ang HJ; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan; Department of Radiation Oncology, National Cheng Kung University Hospital, Tainan, Taiwan. Electronic address: hjmc@nhri.org.tw.

Biochim Biophys Acta ; 1843(9): 2129-37, 2014 Sep.

Article in En | MEDLINE | ID: mdl-24946134

Subject(s)

Colonic Neoplasms/enzymology; Colonic Neoplasms/pathology; Focal Adhesion Protein-Tyrosine Kinases/metabolism; Integrin beta1/metabolism; Radiation Tolerance; Stress, Mechanical; Caspases/metabolism; Cell Death/radiation effects; Cell Line, Tumor; Clone Cells; Down-Regulation/radiation effects; G2 Phase/radiation effects; Humans; Mitosis/radiation effects; Proteasome Endopeptidase Complex/metabolism; Proteolysis/radiation effects; Radiation Tolerance/radiation effects; Signal Transduction/radiation effects; Time Factors; Ubiquitination/radiation effects; X-Rays

Key words

FAK; Integrin; Radiation; Shear stress

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Full text: 1 Database: MEDLINE Main subject: Radiation Tolerance / Stress, Mechanical / Colonic Neoplasms / Integrin beta1 / Focal Adhesion Protein-Tyrosine Kinases Limits: Humans Language: En Journal: Biochim Biophys Acta Year: 2014 Type: Article Affiliation country: Taiwan

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