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The antiproliferative response of indole-3-carbinol in human melanoma cells is triggered by an interaction with NEDD4-1 and disruption of wild-type PTEN degradation.
Aronchik, Ida; Kundu, Aishwarya; Quirit, Jeanne G; Firestone, Gary L.
Affiliation
  • Aronchik I; Department of Molecular and Cell Biology and The Cancer Research Laboratory, Univ. of California at Berkeley, Berkeley, CA 94720-3200.
  • Kundu A; Department of Molecular and Cell Biology and The Cancer Research Laboratory, Univ. of California at Berkeley, Berkeley, CA 94720-3200.
  • Quirit JG; Department of Molecular and Cell Biology and The Cancer Research Laboratory, Univ. of California at Berkeley, Berkeley, CA 94720-3200.
  • Firestone GL; Department of Molecular and Cell Biology and The Cancer Research Laboratory, Univ. of California at Berkeley, Berkeley, CA 94720-3200.
Mol Cancer Res ; 12(11): 1621-1634, 2014 Nov.
Article in En | MEDLINE | ID: mdl-25009292
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Full text: 1 Database: MEDLINE Main subject: Ubiquitin-Protein Ligases / PTEN Phosphohydrolase / Endosomal Sorting Complexes Required for Transport / Proteolysis / Indoles / Melanoma Limits: Animals / Humans Language: En Journal: Mol Cancer Res Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2014 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Ubiquitin-Protein Ligases / PTEN Phosphohydrolase / Endosomal Sorting Complexes Required for Transport / Proteolysis / Indoles / Melanoma Limits: Animals / Humans Language: En Journal: Mol Cancer Res Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2014 Type: Article