Assessing essentiality of transketolase in Mycobacterium tuberculosis using an inducible protein degradation system.

Kolly, Gaëlle S; Sala, Claudia; Vocat, Anthony; Cole, Stewart T

Kolly, Gaëlle S; Sala, Claudia; Vocat, Anthony; Cole, Stewart T.

Affiliation

Kolly GS; Ecole Polytechnique Fédérale de Lausanne, Global Health Institute, Lausanne, Switzerland.

FEMS Microbiol Lett ; 358(1): 30-5, 2014 Sep.

Article in En | MEDLINE | ID: mdl-25047872

Subject(s)

Genes, Essential; Mycobacterium tuberculosis/enzymology; Mycobacterium tuberculosis/physiology; Proteolysis; Transketolase/genetics; Transketolase/metabolism; Cell Line; Gene Silencing; Humans; Microbial Viability; Monocytes/microbiology; Mycobacterium tuberculosis/genetics; Mycobacterium tuberculosis/growth & development; Virulence

Key words

Mycobacterium tuberculosis; conditional mutant; transketolase Tkt; tuberculosis

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Full text: 1 Database: MEDLINE Main subject: Transketolase / Genes, Essential / Proteolysis / Mycobacterium tuberculosis Limits: Humans Language: En Journal: FEMS Microbiol Lett Year: 2014 Type: Article Affiliation country: Switzerland

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