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'Carba'-carfentanil (trans isomer): a µ opioid receptor (MOR) partial agonist with a distinct binding mode.
Weltrowska, Grazyna; Lemieux, Carole; Chung, Nga N; Guo, Jason J; Wilkes, Brian C; Schiller, Peter W.
Affiliation
  • Weltrowska G; Laboratory of Chemical Biology and Peptide Research, Clinical Research Institute of Montreal, 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada.
  • Lemieux C; Laboratory of Chemical Biology and Peptide Research, Clinical Research Institute of Montreal, 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada.
  • Chung NN; Laboratory of Chemical Biology and Peptide Research, Clinical Research Institute of Montreal, 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada.
  • Guo JJ; Center for Drug Discovery, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
  • Wilkes BC; Laboratory of Chemical Biology and Peptide Research, Clinical Research Institute of Montreal, 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada.
  • Schiller PW; Laboratory of Chemical Biology and Peptide Research, Clinical Research Institute of Montreal, 110 Pine Avenue West, Montreal, QC H2W 1R7, Canada; Department of Pharmacology, Université de Montréal, Montreal, QC H3C 3J7, Canada. Electronic address: schillp@ircm.qc.ca.
Bioorg Med Chem ; 22(17): 4581-6, 2014 Sep 01.
Article in En | MEDLINE | ID: mdl-25129170
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Full text: 1 Database: MEDLINE Main subject: Fentanyl / Receptors, Opioid, mu Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Type: Article Affiliation country: Canada
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Full text: 1 Database: MEDLINE Main subject: Fentanyl / Receptors, Opioid, mu Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Type: Article Affiliation country: Canada