Melatonin attenuates inflammatory response-induced brain edema in early brain injury following a subarachnoid hemorrhage: a possible role for the regulation of pro-inflammatory cytokines.

Chen, Jingyin; Chen, Gao; Li, Jianru; Qian, Cong; Mo, Hangbo; Gu, Chi; Yan, Feng; Yan, Wei; Wang, Lin

Chen, Jingyin; Chen, Gao; Li, Jianru; Qian, Cong; Mo, Hangbo; Gu, Chi; Yan, Feng; Yan, Wei; Wang, Lin.

Affiliation

Chen J; Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.

J Pineal Res ; 57(3): 340-7, 2014 Oct.

Article in En | MEDLINE | ID: mdl-25187344

Subject(s)

Brain Edema/prevention & control; Brain Injuries/complications; Cytokines/metabolism; Inflammation Mediators/metabolism; Melatonin/administration & dosage; Subarachnoid Hemorrhage/complications; Animals; Brain Edema/etiology; Male; Melatonin/therapeutic use; Rats; Rats, Sprague-Dawley

Key words

blood-brain barrier; brain edema; early brain injury; inflammation; melatonin; subarachnoid hemorrhage

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Full text: 1 Database: MEDLINE Main subject: Subarachnoid Hemorrhage / Brain Edema / Brain Injuries / Cytokines / Inflammation Mediators / Melatonin Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Pineal Res Journal subject: ENDOCRINOLOGIA Year: 2014 Type: Article Affiliation country: China

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