Ultrasound Findings of Intraductal Papillary Neoplasm in Bile Duct and the Added Value of Contrast-Enhanced Ultrasound.
Ultraschall Med
; 36(6): 594-602, 2015 Dec.
Article
in En
| MEDLINE
| ID: mdl-25188491
PURPOSE: To investigate the imaging features of intraductal papillary neoplasm in bile duct (IPNB) on baseline ultrasound and contrast-enhanced ultrasound (CEUS). MATERIALS AND METHODS: The imaging features on baseline ultrasound and CEUS in 16 pathologically proven IPNB lesions in 15 patients were retrospectively analyzed. Real-time contrast specific modes and contrast agent of SonoVue were used for CEUS. RESULTS: Bile duct dilation was present in all patients. The mean lengths for the intraductal papillary adenomas and adenocarcinomas were 2.5â± 1.1 (range, 1.2â-â4.2âcm) and 5.6â±â2.0âcm (range, 3.3â-â9.8âcm) (Pâ=â0.004). Three imaging types of IPNB on ultrasound were depicted: bile duct dilation with intraductal mass (nâ=â8), bile duct dilation without intraductal mass (nâ=â3), and cystic-solid mixed type (nâ=â5). On CEUS, solid components of 13 lesions appeared hyper- (nâ=â12) or iso-enhancement (nâ=â1) in the arterial phase whereas all showed hypo-enhancement in the portal and late phases. For 3 lesions of bile duct dilation without intraductal mass, CEUS showed non-enhancement during all phases. Pre-surgical CEUS and conventional ultrasound made correct diagnoses in 12 (75.0â%) and 5(31.3â%) of 16 IPNBs respectively (Pâ=â0.04). For CECT, correct diagnosis was also achieved in 12 (75.0â%) of 16 lesions (Pâ=â1.00, in comparison with CEUS). CONCLUSIONS: IPNB should be taken into consideration when intraductal mass or cystic-solid mass with bile duct dilation, or remarkable bile duct dilation without intraductal mass, are found on US.âIntraductal mass length >â3.0âcm is more commonly found in malignant IPNB. CEUS might facilitate the diagnosis of IPNB by easily excluding the possibility of commonly found sludge, nonshadowing stones, or blood clots.
Full text:
1
Database:
MEDLINE
Main subject:
Phospholipids
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Sulfur Hexafluoride
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Bile Duct Neoplasms
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Bile Ducts, Intrahepatic
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Image Enhancement
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Carcinoma, Papillary
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Adenoma
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Common Bile Duct Neoplasms
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Contrast Media
Type of study:
Diagnostic_studies
/
Observational_studies
Limits:
Adult
/
Aged
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Female
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Humans
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Male
/
Middle aged
Language:
En
Journal:
Ultraschall Med
Year:
2015
Type:
Article
Affiliation country:
China