Characterization of diffuse fibrosis in the failing human heart via diffusion tensor imaging and quantitative histological validation.

Abdullah, Osama M; Drakos, Stavros G; Diakos, Nikolaos A; Wever-Pinzon, Omar; Kfoury, Abdallah G; Stehlik, Josef; Selzman, Craig H; Reid, Bruce B; Brunisholz, Kim; Verma, Divya Ratan; Myrick, Craig; Sachse, Frank B; Li, Dean Y; Hsu, Edward W

Abdullah, Osama M; Drakos, Stavros G; Diakos, Nikolaos A; Wever-Pinzon, Omar; Kfoury, Abdallah G; Stehlik, Josef; Selzman, Craig H; Reid, Bruce B; Brunisholz, Kim; Verma, Divya Ratan; Myrick, Craig; Sachse, Frank B; Li, Dean Y; Hsu, Edward W.

Affiliation

Abdullah OM; Department of Bioengineering, University of Utah, Salt Lake City, UT, USA.

NMR Biomed ; 27(11): 1378-86, 2014 Nov.

Article in En | MEDLINE | ID: mdl-25200106

Subject(s)

Diffusion Tensor Imaging/methods; Heart Failure/pathology; Myocardium/pathology; Adult; Aged; Anisotropy; Biopsy; Cardiomyopathy, Dilated/complications; Cardiomyopathy, Dilated/pathology; Collagen/analysis; Computer Simulation; Female; Fibrosis; Heart Ventricles/chemistry; Heart Ventricles/pathology; Humans; Male; Middle Aged; Models, Cardiovascular; Monte Carlo Method; Myocardium/chemistry; Young Adult

Key words

DTI; diffuse fibrosis; fractional anisotropy; histological correlation; idiopathic dilated cardiomyopathy; mean diffusivity; non-ischemic heart failure; principal diffusivities

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Full text: 1 Database: MEDLINE Main subject: Diffusion Tensor Imaging / Heart Failure / Myocardium Type of study: Health_economic_evaluation / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: NMR Biomed Journal subject: DIAGNOSTICO POR IMAGEM / MEDICINA NUCLEAR Year: 2014 Type: Article Affiliation country: United States

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