Conditional glucagon receptor overexpression has multi-faceted consequences for beta-cell function.

Omar, Bilal; Sörhede-Winzell, Maria; Ahrén, Bo

Omar, Bilal; Sörhede-Winzell, Maria; Ahrén, Bo.

Affiliation

Omar B; Lund University, Department of Clinical Sciences, Lund, Sweden. Electronic address: Bilal.Omar@med.lu.se.
Sörhede-Winzell M; Lund University, Department of Clinical Sciences, Lund, Sweden.
Ahrén B; Lund University, Department of Clinical Sciences, Lund, Sweden.

Metabolism ; 63(12): 1568-76, 2014 Dec.

Article in En | MEDLINE | ID: mdl-25301258

Subject(s)

Insulin-Secreting Cells/metabolism; Receptors, Glucagon/biosynthesis; Animals; Arginine/pharmacology; Body Weight/drug effects; Carbachol/pharmacology; Glucagon/pharmacology; Glucagon-Like Peptide 1/metabolism; Glucagon-Like Peptide 1/pharmacology; Glucose Tolerance Test; Humans; Hypoglycemic Agents/pharmacology; Insulin/pharmacology; Insulin-Secreting Cells/drug effects; Islets of Langerhans/drug effects; Islets of Langerhans/metabolism; Mice; Mice, Transgenic; Receptors, Glucagon/drug effects; Receptors, Glucagon/genetics; Receptors, Muscarinic/drug effects

Key words

Beta cell function; GLP-1; Glucagon; Insulin

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Full text: 1 Database: MEDLINE Main subject: Receptors, Glucagon / Insulin-Secreting Cells Limits: Animals / Humans Language: En Journal: Metabolism Year: 2014 Type: Article

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