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Ibrutinib interferes with the cell-mediated anti-tumor activities of therapeutic CD20 antibodies: implications for combination therapy.
Da Roit, Fabio; Engelberts, Patrick J; Taylor, Ronald P; Breij, Esther C W; Gritti, Giuseppe; Rambaldi, Alessandro; Introna, Martino; Parren, Paul W H I; Beurskens, Frank J; Golay, Josée.
Affiliation
  • Da Roit F; Center of Cellular Therapy "G. Lanzani", Division of Hematology, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy.
  • Engelberts PJ; Genmab, Utrecht, the Netherlands.
  • Taylor RP; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA.
  • Breij EC; Genmab, Utrecht, the Netherlands.
  • Gritti G; Center of Cellular Therapy "G. Lanzani", Division of Hematology, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy.
  • Rambaldi A; Center of Cellular Therapy "G. Lanzani", Division of Hematology, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy.
  • Introna M; Center of Cellular Therapy "G. Lanzani", Division of Hematology, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy.
  • Parren PW; Genmab, Utrecht, the Netherlands Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
  • Beurskens FJ; Genmab, Utrecht, the Netherlands.
  • Golay J; Center of Cellular Therapy "G. Lanzani", Division of Hematology, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy jgolay@hpg23.it.
Haematologica ; 100(1): 77-86, 2015 Jan.
Article in En | MEDLINE | ID: mdl-25344523
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Full text: 1 Database: MEDLINE Main subject: Purines / Pyrazoles / Pyrimidines / Leukemia, Lymphocytic, Chronic, B-Cell / Lymphoma, B-Cell / Antigens, CD20 / Quinazolinones / Antibodies, Monoclonal / Antibody-Dependent Cell Cytotoxicity Type of study: Observational_studies / Risk_factors_studies Limits: Humans Language: En Journal: Haematologica Year: 2015 Type: Article Affiliation country: Italy
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Purines / Pyrazoles / Pyrimidines / Leukemia, Lymphocytic, Chronic, B-Cell / Lymphoma, B-Cell / Antigens, CD20 / Quinazolinones / Antibodies, Monoclonal / Antibody-Dependent Cell Cytotoxicity Type of study: Observational_studies / Risk_factors_studies Limits: Humans Language: En Journal: Haematologica Year: 2015 Type: Article Affiliation country: Italy