Small-molecule inhibitors of spleen tyrosine kinase as therapeutic agents for immune disorders: will promise meet expectations?

Lucas, Matthew C; Tan, Seng-Lai

Lucas, Matthew C; Tan, Seng-Lai.

Affiliation

Lucas MC; Cubist Pharmaceuticals, 65 Hayden Avenue, Lexington, MA 02421, USA.

Future Med Chem ; 6(16): 1811-27, 2014.

Article in En | MEDLINE | ID: mdl-25407369

Subject(s)

Immune System Diseases/drug therapy; Protein Kinase Inhibitors/pharmacology; Protein-Tyrosine Kinases/antagonists & inhibitors; Small Molecule Libraries/pharmacology; Spleen/drug effects; Spleen/enzymology; Humans; Immune System Diseases/metabolism; Molecular Structure; Protein Kinase Inhibitors/chemistry; Protein-Tyrosine Kinases/metabolism; Small Molecule Libraries/chemistry

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Full text: 1 Database: MEDLINE Main subject: Spleen / Protein-Tyrosine Kinases / Protein Kinase Inhibitors / Small Molecule Libraries / Immune System Diseases Limits: Humans Language: En Journal: Future Med Chem Year: 2014 Type: Article Affiliation country: United States

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