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The effect of pK(a) on pyrimidine/pyridine-derived histamine H4 ligands.
Savall, Brad M; Meduna, Steven P; Venable, Jennifer; Wei, Jianmei; Smith, Russell C; Hack, Michael D; Thurmond, Robin L; McGovern, Patricia; Edwards, James P.
Affiliation
  • Savall BM; Janssen Pharmaceutical Research & Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, United States.
  • Meduna SP; Janssen Pharmaceutical Research & Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, United States.
  • Venable J; Janssen Pharmaceutical Research & Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, United States.
  • Wei J; Janssen Pharmaceutical Research & Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, United States.
  • Smith RC; Janssen Pharmaceutical Research & Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, United States.
  • Hack MD; Janssen Pharmaceutical Research & Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, United States.
  • Thurmond RL; Janssen Pharmaceutical Research & Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, United States.
  • McGovern P; Janssen Pharmaceutical Research & Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, United States.
  • Edwards JP; Janssen Pharmaceutical Research & Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, United States.
Bioorg Med Chem Lett ; 24(23): 5489-92, 2014 Dec 01.
Article in En | MEDLINE | ID: mdl-25455490
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Full text: 1 Database: MEDLINE Main subject: Pyridines / Pyrimidines / Receptors, Histamine / Receptors, G-Protein-Coupled / Histamine Antagonists Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Pyridines / Pyrimidines / Receptors, Histamine / Receptors, G-Protein-Coupled / Histamine Antagonists Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Type: Article Affiliation country: United States