Inhaled hydrogen sulfide prevents neuropathic pain after peripheral nerve injury in mice.

Kida, Kotaro; Marutani, Eizo; Nguyen, Rebecca K; Ichinose, Fumito

Kida, Kotaro; Marutani, Eizo; Nguyen, Rebecca K; Ichinose, Fumito.

Affiliation

Kida K; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Marutani E; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Nguyen RK; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Ichinose F; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: fichinose@mgh.harvard.edu.

Nitric Oxide ; 46: 87-92, 2015 Apr 30.

Article in En | MEDLINE | ID: mdl-25461302

Subject(s)

Analgesics/pharmacology; Hydrogen Sulfide/pharmacology; Peripheral Nerve Injuries/drug therapy; Sciatic Nerve/injuries; Administration, Inhalation; Animals; Behavior, Animal/drug effects; Hyperalgesia; Interleukin-6/metabolism; Male; Mice; Mice, Inbred C57BL; Microglia/drug effects; Pain Management/methods; Peripheral Nerve Injuries/physiopathology; Rats, Sprague-Dawley; Sciatic Nerve/drug effects; Spinal Cord/chemistry; Spinal Cord/drug effects; Spinal Cord/metabolism

Key words

Hydrogen sulfide; Inflammatory cytokine; Microglia; Neuropathic pain

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Full text: 1 Database: MEDLINE Main subject: Sciatic Nerve / Peripheral Nerve Injuries / Hydrogen Sulfide / Analgesics Limits: Animals Language: En Journal: Nitric Oxide Journal subject: BIOQUIMICA / QUIMICA Year: 2015 Type: Article Affiliation country: United States

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