Ameliorative potential of ferulic acid in vincristine-induced painful neuropathy in rats: An evidence of behavioral and biochemical examination.

Vashistha, Bharat; Sharma, Abhisheak; Jain, Vivek

Vashistha, Bharat; Sharma, Abhisheak; Jain, Vivek.

Affiliation

Vashistha B; a Department of Pharmacology , Gyan Vihar School of Pharmacy, Suresh Gyan Vihar University , Jaipur , Rajasthan , India.
Sharma A; b Department of Dravyaguna Vigyan , National Institute of Ayurveda , Jaipur , Rajasthan , India.
Jain V; c Department of Pharmacy , Banasthali University , Banasthali , Rajasthan , India.

Nutr Neurosci ; 20(1): 60-70, 2017 Jan.

Article in En | MEDLINE | ID: mdl-25494651

Subject(s)

Antineoplastic Agents, Phytogenic/adverse effects; Coumaric Acids/therapeutic use; Neuroprotective Agents/therapeutic use; Neurotoxicity Syndromes/drug therapy; Pain/prevention & control; Peripheral Nervous System Diseases/prevention & control; Vincristine/adverse effects; Animals; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use; Behavior, Animal/drug effects; Biomarkers/metabolism; Coumaric Acids/administration & dosage; Dose-Response Relationship, Drug; Female; Free Radical Scavengers/therapeutic use; Injections, Intraperitoneal; Lipid Peroxidation/drug effects; Male; Motor Neurons/drug effects; Motor Neurons/immunology; Motor Neurons/metabolism; Neural Conduction/drug effects; Neuroprotective Agents/administration & dosage; Neurotoxicity Syndromes/immunology; Neurotoxicity Syndromes/metabolism; Neurotoxicity Syndromes/physiopathology; Oxidative Stress/drug effects; Pain/etiology; Peripheral Nervous System Diseases/etiology; Rats, Wistar; Sciatic Nerve/drug effects; Sciatic Nerve/immunology; Sciatic Nerve/metabolism; Sciatic Nerve/pathology; Sensory Receptor Cells/drug effects; Sensory Receptor Cells/immunology; Sensory Receptor Cells/metabolism

Key words

Ferulic acid; IL-10; IL-6; Neuropathic pain; TNF-alpha; Vincristine

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Full text: 1 Database: MEDLINE Main subject: Pain / Vincristine / Peripheral Nervous System Diseases / Neuroprotective Agents / Coumaric Acids / Neurotoxicity Syndromes / Antineoplastic Agents, Phytogenic Type of study: Etiology_studies Language: En Journal: Nutr Neurosci Journal subject: CIENCIAS DA NUTRICAO / NEUROLOGIA Year: 2017 Type: Article Affiliation country: India

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