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Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity.
Bruncko, Milan; Wang, Le; Sheppard, George S; Phillips, Darren C; Tahir, Stephen K; Xue, John; Erickson, Scott; Fidanze, Steve; Fry, Elizabeth; Hasvold, Lisa; Jenkins, Gary J; Jin, Sha; Judge, Russell A; Kovar, Peter J; Madar, David; Nimmer, Paul; Park, Chang; Petros, Andrew M; Rosenberg, Saul H; Smith, Morey L; Song, Xiaohong; Sun, Chaohong; Tao, Zhi-Fu; Wang, Xilu; Xiao, Yu; Zhang, Haichao; Tse, Chris; Leverson, Joel D; Elmore, Steven W; Souers, Andrew J.
Affiliation
  • Bruncko M; AbbVie Inc. , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
J Med Chem ; 58(5): 2180-94, 2015 Mar 12.
Article in En | MEDLINE | ID: mdl-25679114
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Full text: 1 Database: MEDLINE Main subject: Pancreatic Neoplasms / Drug Design / Myeloid Cell Leukemia Sequence 1 Protein / Multiple Myeloma / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2015 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Pancreatic Neoplasms / Drug Design / Myeloid Cell Leukemia Sequence 1 Protein / Multiple Myeloma / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2015 Type: Article Affiliation country: United States