Immunomodulatory role of piperine in deltamethrin induced thymic apoptosis and altered immune functions.

Kumar, Anoop; Sasmal, D; Sharma, Neelima

Kumar, Anoop; Sasmal, D; Sharma, Neelima.

Affiliation

Kumar A; Department of Pharmaceutical Science and Technology, Birla Institute of Technology, Mesra, Ranchi, 835215, Jharkhand, India.
Sasmal D; Department of Pharmaceutical Science and Technology, Birla Institute of Technology, Mesra, Ranchi, 835215, Jharkhand, India.
Sharma N; Department of Pharmaceutical Science and Technology, Birla Institute of Technology, Mesra, Ranchi, 835215, Jharkhand, India. Electronic address: nsharmabit@gmail.com.

Environ Toxicol Pharmacol ; 39(2): 504-14, 2015 Mar.

Article in En | MEDLINE | ID: mdl-25682002

Subject(s)

Alkaloids/pharmacology; Antioxidants/pharmacology; Benzodioxoles/pharmacology; Immunologic Factors/pharmacology; Nitriles/toxicity; Piperidines/pharmacology; Polyunsaturated Alkamides/pharmacology; Pyrethrins/toxicity; Thymocytes/drug effects; Animals; Apoptosis/drug effects; CD4 Antigens/metabolism; Caspase 3/metabolism; Cell Survival/drug effects; Glutathione/metabolism; Interferon-gamma/metabolism; Interleukin-2/metabolism; Interleukin-4/metabolism; Male; Mice, Inbred BALB C; Molecular Docking Simulation; Reactive Oxygen Species/metabolism; Receptors, Antigen, T-Cell/metabolism; Thymocytes/metabolism

Key words

Apoptosis; Deltamethrin; Oxidative stress; Phenotyping; Piperine

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Full text: 1 Database: MEDLINE Main subject: Piperidines / Pyrethrins / Alkaloids / Benzodioxoles / Polyunsaturated Alkamides / Thymocytes / Immunologic Factors / Nitriles / Antioxidants Limits: Animals Language: En Journal: Environ Toxicol Pharmacol Year: 2015 Type: Article Affiliation country: India

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