Impact on prognosis of the regional distribution of MGMT methylation with respect to the CpG island methylator phenotype and age in glioma patients.

Mur, Pilar; Rodríguez de Lope, Ángel; Díaz-Crespo, Francisco Javier; Hernández-Iglesias, Teresa; Ribalta, Teresa; Fiaño, Concepción; García, Juan Fernando; Rey, Juan Antonio; Mollejo, Manuela; Meléndez, Bárbara

Mur, Pilar; Rodríguez de Lope, Ángel; Díaz-Crespo, Francisco Javier; Hernández-Iglesias, Teresa; Ribalta, Teresa; Fiaño, Concepción; García, Juan Fernando; Rey, Juan Antonio; Mollejo, Manuela; Meléndez, Bárbara.

Affiliation

Mur P; Molecular Pathology Research Unit, Department of Pathology, Virgen de la Salud Hospital, Avda Barber 30, 45004, Toledo, Spain.

J Neurooncol ; 122(3): 441-50, 2015 May.

Article in En | MEDLINE | ID: mdl-25682093

Subject(s)

Brain Neoplasms/genetics; CpG Islands/genetics; DNA Methylation/genetics; DNA Modification Methylases/genetics; DNA Repair Enzymes/genetics; Glioma/genetics; Tumor Suppressor Proteins/genetics; Adult; Age Factors; Aged; Brain Neoplasms/diagnosis; Brain Neoplasms/mortality; Female; Gene Expression Profiling; Glioma/diagnosis; Glioma/mortality; Humans; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Phenotype; Principal Component Analysis; Prognosis; Promoter Regions, Genetic/genetics; Survival Analysis; Young Adult

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Full text: 1 Database: MEDLINE Main subject: Brain Neoplasms / DNA Modification Methylases / CpG Islands / DNA Methylation / Tumor Suppressor Proteins / DNA Repair Enzymes / Glioma Type of study: Diagnostic_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: J Neurooncol Year: 2015 Type: Article Affiliation country: Spain

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