Phosphopeptide interactions with BRCA1 BRCT domains: More than just a motif.

Wu, Qian; Jubb, Harry; Blundell, Tom L

Wu, Qian; Jubb, Harry; Blundell, Tom L.

Affiliation

Wu Q; Department of Biochemistry, 80 Tennis Court Road, University of Cambridge, CB2 1GA, Cambridge, United Kingdom. Electronic address: qw222@cam.ac.uk.
Jubb H; Department of Biochemistry, 80 Tennis Court Road, University of Cambridge, CB2 1GA, Cambridge, United Kingdom.
Blundell TL; Department of Biochemistry, 80 Tennis Court Road, University of Cambridge, CB2 1GA, Cambridge, United Kingdom.

Prog Biophys Mol Biol ; 117(2-3): 143-148, 2015 Mar.

Article in En | MEDLINE | ID: mdl-25701377

Subject(s)

BRCA1 Protein/chemistry; BRCA1 Protein/ultrastructure; DNA Damage/physiology; Models, Chemical; Models, Molecular; Phosphopeptides/chemistry; Amino Acid Motifs; Amino Acid Sequence; BRCA1 Protein/metabolism; Binding Sites; Computer Simulation; DNA Repair/physiology; Molecular Sequence Data; Phosphopeptides/metabolism; Protein Binding; Protein Conformation; Protein Structure, Tertiary

Key words

BRCA1; BRCT; DNA damage response; Phosphopeptide; Tandem BRCT domains; pSXXF motif

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Full text: 1 Database: MEDLINE Main subject: Phosphopeptides / DNA Damage / Models, Molecular / BRCA1 Protein / Models, Chemical Language: En Journal: Prog Biophys Mol Biol Year: 2015 Type: Article

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