Identification of hemoglobin variants by top-down mass spectrometry using selected diagnostic product ions.

Coelho Graça, Didia; Hartmer, Ralf; Jabs, Wolfgang; Beris, Photis; Clerici, Lorella; Stoermer, Carsten; Samii, Kaveh; Hochstrasser, Denis; Tsybin, Yury O; Scherl, Alexander; Lescuyer, Pierre

Coelho Graça, Didia; Hartmer, Ralf; Jabs, Wolfgang; Beris, Photis; Clerici, Lorella; Stoermer, Carsten; Samii, Kaveh; Hochstrasser, Denis; Tsybin, Yury O; Scherl, Alexander; Lescuyer, Pierre.

Affiliation

Coelho Graça D; Department of Human Protein Sciences, Faculty of Medicine, Geneva University, Rue Michel Servet 1, 1211, Geneva, Switzerland.

Anal Bioanal Chem ; 407(10): 2837-45, 2015 Apr.

Article in En | MEDLINE | ID: mdl-25753013

Subject(s)

Hemoglobins/analysis; Mass Spectrometry/methods; Amino Acid Sequence; Fetal Hemoglobin/analysis; Fetal Hemoglobin/genetics; Gene Fusion; Genetic Variation; Hemoglobins/genetics; Hemoglobins, Abnormal/analysis; Hemoglobins, Abnormal/genetics; Humans; Molecular Sequence Data; Mutation; Tandem Mass Spectrometry/methods; Workflow; beta-Globins/analysis; beta-Globins/genetics

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Full text: 1 Database: MEDLINE Main subject: Mass Spectrometry / Hemoglobins Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Anal Bioanal Chem Year: 2015 Type: Article Affiliation country: Switzerland

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