Cytokine-induced killer cells engineered with exogenous T-cell receptors directed against melanoma antigens: enhanced efficacy of effector cells endowed with a double mechanism of tumor recognition.

Elia, Angela R; Circosta, Paola; Sangiolo, Dario; Bonini, Chiara; Gammaitoni, Loretta; Mastaglio, Sara; Genovese, Pietro; Geuna, Massimo; Avolio, Fabio; Inghirami, Giorgio; Tarella, Corrado; Cignetti, Alessandro

Elia, Angela R; Circosta, Paola; Sangiolo, Dario; Bonini, Chiara; Gammaitoni, Loretta; Mastaglio, Sara; Genovese, Pietro; Geuna, Massimo; Avolio, Fabio; Inghirami, Giorgio; Tarella, Corrado; Cignetti, Alessandro.

Affiliation

Elia AR; 1 Molecular Biotechnology Center, University of Torino , 10126 Turin, Italy .

Hum Gene Ther ; 26(4): 220-31, 2015 Apr.

Article in En | MEDLINE | ID: mdl-25758764

Subject(s)

B-Lymphocyte Subsets/immunology; Cytokines/physiology; Melanoma/therapy; Natural Killer T-Cells/immunology; Receptors, Antigen, T-Cell/biosynthesis; Antigens, Neoplasm/immunology; Cell Line, Tumor; Genetic Engineering; Humans; Immunotherapy, Adoptive; Leukocytes, Mononuclear/immunology; Melanoma/immunology; Receptors, Antigen, T-Cell/genetics

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Full text: 1 Database: MEDLINE Main subject: Receptors, Antigen, T-Cell / Cytokines / B-Lymphocyte Subsets / Natural Killer T-Cells / Melanoma Limits: Humans Language: En Journal: Hum Gene Ther Journal subject: GENETICA MEDICA / TERAPEUTICA Year: 2015 Type: Article Affiliation country: Italy

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