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Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease.
Lee, Dong I; Zhu, Guangshuo; Sasaki, Takashi; Cho, Gun-Sik; Hamdani, Nazha; Holewinski, Ronald; Jo, Su-Hyun; Danner, Thomas; Zhang, Manling; Rainer, Peter P; Bedja, Djahida; Kirk, Jonathan A; Ranek, Mark J; Dostmann, Wolfgang R; Kwon, Chulan; Margulies, Kenneth B; Van Eyk, Jennifer E; Paulus, Walter J; Takimoto, Eiki; Kass, David A.
Affiliation
  • Lee DI; Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.
  • Zhu G; Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.
  • Sasaki T; Advanced Medical Research Laboratories, Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Kanagawa 227-0033, Japan.
  • Cho GS; Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.
  • Hamdani N; Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.
  • Holewinski R; 1] Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA [2] Heart Institute and Advanced Clinical Biosystems Research Institute, Cedar Sinai Medical Center, 8700 Beverly Blvd, AHSP A9229 Los Angeles, California 90048, USA.
  • Jo SH; Department of Physiology, Institute of Bioscience and Biotechnology, BK21 plus Graduate Program, Kangwon National University College of Medicine, Chuncheon 200-701, Korea.
  • Danner T; Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.
  • Zhang M; Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.
  • Rainer PP; Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.
  • Bedja D; Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.
  • Kirk JA; Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.
  • Ranek MJ; Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.
  • Dostmann WR; Department of Pharmacology, University of Vermont, Burlington, Vermont 05405, USA.
  • Kwon C; Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.
  • Margulies KB; Department of Medicine, Division of Cardiovascular Medicine, Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
  • Van Eyk JE; 1] Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA [2] Heart Institute and Advanced Clinical Biosystems Research Institute, Cedar Sinai Medical Center, 8700 Beverly Blvd, AHSP A9229 Los Angeles, California 90048, USA.
  • Paulus WJ; Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.
  • Takimoto E; Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.
  • Kass DA; Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA.
Nature ; 519(7544): 472-6, 2015 Mar 26.
Article in En | MEDLINE | ID: mdl-25799991
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Full text: 1 Database: MEDLINE Main subject: Cardiomegaly / 3',5'-Cyclic-AMP Phosphodiesterases / Cyclic GMP / Nitric Oxide Type of study: Etiology_studies Limits: Animals / Humans / Male Language: En Journal: Nature Year: 2015 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Cardiomegaly / 3',5'-Cyclic-AMP Phosphodiesterases / Cyclic GMP / Nitric Oxide Type of study: Etiology_studies Limits: Animals / Humans / Male Language: En Journal: Nature Year: 2015 Type: Article Affiliation country: United States