Protective effect of berberine against myocardial ischemia reperfusion injury: role of Notch1/Hes1-PTEN/Akt signaling.

Yu, Liming; Li, Feijiang; Zhao, Guolong; Yang, Yang; Jin, Zhenxiao; Zhai, Mengen; Yu, Wenjun; Zhao, Lin; Chen, Wensheng; Duan, Weixun; Yu, Shiqiang

Yu, Liming; Li, Feijiang; Zhao, Guolong; Yang, Yang; Jin, Zhenxiao; Zhai, Mengen; Yu, Wenjun; Zhao, Lin; Chen, Wensheng; Duan, Weixun; Yu, Shiqiang.

Affiliation

Yu L; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, 127 Changle West Road, Xi'an, 710032, China.

Apoptosis ; 20(6): 796-810, 2015 Jun.

Article in En | MEDLINE | ID: mdl-25824534

Subject(s)

Basic Helix-Loop-Helix Transcription Factors/metabolism; Berberine/pharmacology; Homeodomain Proteins/metabolism; Myocardial Reperfusion Injury/metabolism; Oncogene Protein v-akt/metabolism; PTEN Phosphohydrolase/metabolism; Receptor, Notch1/metabolism; Signal Transduction/drug effects; Animals; Apoptosis/drug effects; Cell Survival/drug effects; Chromones/metabolism; Enzyme Inhibitors/metabolism; Male; Morpholines/metabolism; Myocardial Reperfusion Injury/prevention & control; Myocardium/metabolism; Myocytes, Cardiac; RNA, Small Interfering/metabolism; Rats, Sprague-Dawley; Transcription Factor HES-1

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Full text: 1 Database: MEDLINE Main subject: Berberine / Myocardial Reperfusion Injury / Signal Transduction / Homeodomain Proteins / PTEN Phosphohydrolase / Oncogene Protein v-akt / Basic Helix-Loop-Helix Transcription Factors / Receptor, Notch1 Limits: Animals Language: En Journal: Apoptosis Year: 2015 Type: Article Affiliation country: China

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