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α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation.
Wang, Shijun; Chu, Chun-Hsien; Stewart, Tessandra; Ginghina, Carmen; Wang, Yifei; Nie, Hui; Guo, Mingri; Wilson, Belinda; Hong, Jau-Shyong; Zhang, Jing.
Affiliation
  • Wang S; Department of Pathology, University of Washington School of Medicine, Seattle, WA 98104; Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709;
  • Chu CH; Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709;
  • Stewart T; Department of Pathology, University of Washington School of Medicine, Seattle, WA 98104;
  • Ginghina C; Department of Pathology, University of Washington School of Medicine, Seattle, WA 98104;
  • Wang Y; East Chapel Hill High School, Chapel Hill, NC 27514; Division of Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599; and.
  • Nie H; Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709;
  • Guo M; Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709;
  • Wilson B; Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709;
  • Hong JS; Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709;
  • Zhang J; Department of Pathology, University of Washington School of Medicine, Seattle, WA 98104; Department of Pathology, Peking University Third Hospital and School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China zhangj@u.washington.edu.
Proc Natl Acad Sci U S A ; 112(15): E1926-35, 2015 Apr 14.
Article in En | MEDLINE | ID: mdl-25825709
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Full text: 1 Database: MEDLINE Main subject: Cell Movement / Microglia / Src-Family Kinases / Alpha-Synuclein / Hydrogen Peroxide Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2015 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Cell Movement / Microglia / Src-Family Kinases / Alpha-Synuclein / Hydrogen Peroxide Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2015 Type: Article