Quantitative proteomics of heat-treated human cells show an across-the-board mild depletion of housekeeping proteins to massively accumulate few HSPs.

Finka, Andrija; Sood, Vishal; Quadroni, Manfredo; Rios, Paolo De Los; Goloubinoff, Pierre

Finka, Andrija; Sood, Vishal; Quadroni, Manfredo; Rios, Paolo De Los; Goloubinoff, Pierre.

Affiliation

Finka A; Department of Plant Molecular Biology, Faculty of Biology and Medicine, University of Lausanne, 1015, Lausanne, Switzerland.

Cell Stress Chaperones ; 20(4): 605-20, 2015 Jul.

Article in En | MEDLINE | ID: mdl-25847399

Subject(s)

Heat-Shock Proteins/metabolism; Proteomics; Benzoquinones/toxicity; Chromatography, High Pressure Liquid; HSC70 Heat-Shock Proteins/genetics; HSC70 Heat-Shock Proteins/metabolism; HSP70 Heat-Shock Proteins/genetics; HSP70 Heat-Shock Proteins/metabolism; HSP90 Heat-Shock Proteins/genetics; HSP90 Heat-Shock Proteins/metabolism; Heat-Shock Proteins/genetics; Humans; Isotope Labeling; Jurkat Cells; Lactams, Macrocyclic/toxicity; Mass Spectrometry; RNA, Messenger/metabolism; Temperature; Transcriptome/drug effects

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Full text: 1 Database: MEDLINE Main subject: Proteomics / Heat-Shock Proteins Limits: Humans Language: En Journal: Cell Stress Chaperones Year: 2015 Type: Article Affiliation country: Switzerland

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