Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.

Cortez, Leonardo M; Campeau, Jody; Norman, Grant; Kalayil, Marian; Van der Merwe, Jacques; McKenzie, Debbie; Sim, Valerie L

Cortez, Leonardo M; Campeau, Jody; Norman, Grant; Kalayil, Marian; Van der Merwe, Jacques; McKenzie, Debbie; Sim, Valerie L.

J Virol ; 89(15): 7660-72, 2015 Aug.

Article in En | MEDLINE | ID: mdl-25972546

Subject(s)

Neurons/metabolism; PrPC Proteins/metabolism; PrPSc Proteins/metabolism; Prion Diseases/metabolism; Prion Diseases/physiopathology; Taurochenodeoxycholic Acid/metabolism; Ursodeoxycholic Acid/metabolism; Animals; Bile Acids and Salts/metabolism; Cell Death; Cell Survival; Female; Humans; Male; Mice; Mice, Inbred C57BL; Neurons/cytology; Species Specificity

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Taurochenodeoxycholic Acid / Ursodeoxycholic Acid / Prion Diseases / PrPSc Proteins / PrPC Proteins / Neurons Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: J Virol Year: 2015 Type: Article

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google