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The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex.
Seefeldt, A Carolin; Nguyen, Fabian; Antunes, Stéphanie; Pérébaskine, Natacha; Graf, Michael; Arenz, Stefan; Inampudi, K Kishore; Douat, Céline; Guichard, Gilles; Wilson, Daniel N; Innis, C Axel.
Affiliation
  • Seefeldt AC; 1] Institut Européen de Chimie et Biologie, Université de Bordeaux, Pessac, France. [2] INSERM U869, Bordeaux, France.
  • Nguyen F; Gene Center, Department of Biochemistry, University of Munich, Munich, Germany.
  • Antunes S; 1] Institut Européen de Chimie et Biologie, Université de Bordeaux, Pessac, France. [2] Université de Bordeaux, CNRS, Institut Polytechnique de Bordeaux, UMR 5248, Institut de Chimie et Biologie des Membranes et des Nano-objets (CBMN), Pessac, France.
  • Pérébaskine N; 1] Institut Européen de Chimie et Biologie, Université de Bordeaux, Pessac, France. [2] INSERM U869, Bordeaux, France.
  • Graf M; Gene Center, Department of Biochemistry, University of Munich, Munich, Germany.
  • Arenz S; Gene Center, Department of Biochemistry, University of Munich, Munich, Germany.
  • Inampudi KK; 1] Institut Européen de Chimie et Biologie, Université de Bordeaux, Pessac, France. [2] INSERM U869, Bordeaux, France.
  • Douat C; 1] Institut Européen de Chimie et Biologie, Université de Bordeaux, Pessac, France. [2] Université de Bordeaux, CNRS, Institut Polytechnique de Bordeaux, UMR 5248, Institut de Chimie et Biologie des Membranes et des Nano-objets (CBMN), Pessac, France.
  • Guichard G; 1] Institut Européen de Chimie et Biologie, Université de Bordeaux, Pessac, France. [2] Université de Bordeaux, CNRS, Institut Polytechnique de Bordeaux, UMR 5248, Institut de Chimie et Biologie des Membranes et des Nano-objets (CBMN), Pessac, France.
  • Wilson DN; 1] Gene Center, Department of Biochemistry, University of Munich, Munich, Germany. [2] Center for Integrated Protein Science Munich (CiPSM), University of Munich, Munich, Germany.
  • Innis CA; 1] Institut Européen de Chimie et Biologie, Université de Bordeaux, Pessac, France. [2] INSERM U869, Bordeaux, France.
Nat Struct Mol Biol ; 22(6): 470-5, 2015 Jun.
Article in En | MEDLINE | ID: mdl-25984971
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Full text: 1 Database: MEDLINE Main subject: Peptide Chain Initiation, Translational / Ribosomes / Protein Synthesis Inhibitors / Antimicrobial Cationic Peptides Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Nat Struct Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2015 Type: Article Affiliation country: France
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Full text: 1 Database: MEDLINE Main subject: Peptide Chain Initiation, Translational / Ribosomes / Protein Synthesis Inhibitors / Antimicrobial Cationic Peptides Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Nat Struct Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2015 Type: Article Affiliation country: France