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PI3 kinase is indispensable for oncogenic transformation by the V560D mutant of c-Kit in a kinase-independent manner.
Lindblad, Oscar; Kazi, Julhash U; Rönnstrand, Lars; Sun, Jianmin.
Affiliation
  • Lindblad O; Division of Translational Cancer Research and Lund Stem Cell Center, Department of Laboratory Medicine, Lund University, Medicon Village 404C3, Scheelevägen 8, 22363, Lund, Sweden.
  • Kazi JU; Division of Translational Cancer Research and Lund Stem Cell Center, Department of Laboratory Medicine, Lund University, Medicon Village 404C3, Scheelevägen 8, 22363, Lund, Sweden.
  • Rönnstrand L; Division of Translational Cancer Research and Lund Stem Cell Center, Department of Laboratory Medicine, Lund University, Medicon Village 404C3, Scheelevägen 8, 22363, Lund, Sweden.
  • Sun J; Division of Translational Cancer Research and Lund Stem Cell Center, Department of Laboratory Medicine, Lund University, Medicon Village 404C3, Scheelevägen 8, 22363, Lund, Sweden. jianmin.sun@med.lu.se.
Cell Mol Life Sci ; 72(22): 4399-407, 2015 Nov.
Article in En | MEDLINE | ID: mdl-26040420

Full text: 1 Database: MEDLINE Main subject: Cell Transformation, Neoplastic / Proto-Oncogene Proteins c-kit / Phosphatidylinositol 3-Kinases / Mutation, Missense Limits: Animals / Humans Language: En Journal: Cell Mol Life Sci Journal subject: BIOLOGIA MOLECULAR Year: 2015 Type: Article Affiliation country: Sweden

Full text: 1 Database: MEDLINE Main subject: Cell Transformation, Neoplastic / Proto-Oncogene Proteins c-kit / Phosphatidylinositol 3-Kinases / Mutation, Missense Limits: Animals / Humans Language: En Journal: Cell Mol Life Sci Journal subject: BIOLOGIA MOLECULAR Year: 2015 Type: Article Affiliation country: Sweden