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A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase.
Killedar, Anagha; Stutz, Michael D; Sobinoff, Alexander P; Tomlinson, Christopher G; Bryan, Tracy M; Beesley, Jonathan; Chenevix-Trench, Georgia; Reddel, Roger R; Pickett, Hilda A.
Affiliation
  • Killedar A; Telomere Length Regulation Group, Children's Medical Research Institute, University of Sydney, Westmead, New South Wales, Australia.
  • Stutz MD; Telomere Length Regulation Group, Children's Medical Research Institute, University of Sydney, Westmead, New South Wales, Australia.
  • Sobinoff AP; Telomere Length Regulation Group, Children's Medical Research Institute, University of Sydney, Westmead, New South Wales, Australia.
  • Tomlinson CG; Cell Biology Unit, Children's Medical Research Institute, University of Sydney, Westmead, New South Wales, Australia.
  • Bryan TM; Cell Biology Unit, Children's Medical Research Institute, University of Sydney, Westmead, New South Wales, Australia.
  • Beesley J; Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Chenevix-Trench G; Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Reddel RR; Cancer Research Unit, Children's Medical Research Institute, University of Sydney, Westmead, New South Wales, Australia.
  • Pickett HA; Telomere Length Regulation Group, Children's Medical Research Institute, University of Sydney, Westmead, New South Wales, Australia.
PLoS Genet ; 11(6): e1005286, 2015 Jun.
Article in En | MEDLINE | ID: mdl-26053551
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Full text: 1 Database: MEDLINE Main subject: Ovarian Neoplasms / Breast Neoplasms / Carcinoma / Telomerase / Alleles Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2015 Type: Article Affiliation country: Australia
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Ovarian Neoplasms / Breast Neoplasms / Carcinoma / Telomerase / Alleles Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2015 Type: Article Affiliation country: Australia